Rationale, Aims and objectives The management of vaginal health care in general practice settings is performing suboptimal. Vaginal complaints are of frequent and recurrent nature and often stay untreated or are maltreated. eHealth and increased empowerment of patients offer opportunities to improve vaginal health care offered by GPs. The aim is to develop and evaluate an e-tool for women with vaginal complaints, for improving vaginal health care. With this e-tool women can estimate the necessity to schedule a GP consult, wait, or self-diagnose and self-treat. Methods For this qualitative study, the setting is a large general practitioners’ office in the Netherlands. After developing the electronic decision aid, we used a purposive sample of 10 women of different ages, to evaluate the e-tool. The data was collected through semi-structured and cognitive interviews, encouraging the thinking aloud method. The interviews were processed with thematic content analysis. Information about (dis)satisfaction was obtained with comparing expectations and perceptions of the subsets content, development process and effectiveness of the e-tool. Results Besides providing information, the e-tool enables women to self-structure their symptoms and prepare them for consultation with their GP (if necessary) or self-diagnose and self-treat (if appropriate). Although in general the women were satisfied, we also got various tips for improvement and further refinement of this electronic decision aid. Conclusions To the best of our knowlegde, this is the first, scientifically developed, (prototype) of an e-tool for self-diagnosis and treatment of vaginal complaints. In the near future, implementing an e-tool for vaginal complaints in general practice, seems promising in making vaginal health care more effective and efficient.