Good scientific communication is helpful in improvement of cardiovascular health and life due to a number of scientific highlights and conducting the outcomes of both basic studies and clinical trials in cardiovascular disease (CVD). In this article, the author proposed new concepts of scientific communication from conferences/clinical to clinical/conferences (Co2Cl & Cl2Co), discusses related roles in clinical practice and translational studies as well as scientific innovation. Since international scientific conferences or congresses focus on prevention, health promotion, education and training as well as treatment or management and rehabilitation of CVD, Co2Cl & Cl2Co are beneficial to improvement of cardiovascular health and quality of life due to a number of scientific breakthroughs and a series of discoveries in cardiovascular medicine. Both models of Co2Cl & Cl2Co contribute to better cardiovascular scientific communication, excellent clinical practice and translational research as well as better scientific innovation, in particular the pandemic and post-COVID-19 era.