In chemistry, the intrinsic limitation to 2-dimensional publishing in displaying molecular structures of the PDF format limits the understandability of the research \cite{Fatemah_2020}.  The three dimensional shape or configuration of a molecule is an important characteristic and it is of paramount importance to understand the compound's reactivity, properties, and characteristics, including toxicity.  
3D interactive visualization of molecular structures have been employed for decades in chemistry to analyze and display research results \cite{Ihlenfeldt_1998}, but this web-ready application did not make it into mainstream academic publications due to their print-first focus. In fact, one can argue that 2D representation of molecules is not part of the research toolkit in chemistry for two decades at least and would have but all disappeared if it weren't for scientific journals. Now the same tools that are at the disposal of researchers when analyzing their data can be finally offered to readers, speeding up the impact of the research.