Results
Among the total of 7 trials, 2 trials demonstrated a positive association between PEs and PI in short (≤ 6 weeks) and long term (> 6 months), while another 2 trials demonstrated no association at medium term (> 6 weeks - ≤ 6 months). About 4 trials demonstrated a positive significant association between PEs and LF, 2 at medium and 2 at long terms. The only available trial demonstrated no association between PEs and HRQOL at medium term.