Figure 8. Quercitrin is important for cerebral ischemia/reperfusion injury in vivo.
Cerebral ischemia/reperfusion injury was induced as described in Methods. (A) Representative pictures of brain sections stained with 2,3,5-triphenyl tetrazolium chloride. (B) The infarct volume was measured by Image J. (C) The Neurological deficit score test was used to analyze neurological behavior disorder in the surviving animals 24 hours after MCAO and reperfusion. Neurological findings were scored in a 5-point scale as follows: no neurological deficit=0, failure to extend right forepaw fully=1, circling to the right=2, falling to extend right=3 and no spontaneous walking with a depressed level of consciousness=4. The bars represent the median of the interquartile range for each group of animals (n = 5). *:P<0.05 and ***:P<0.001 versus vehicle control after ANOVA and Turkey’s test.