Introduction
Tuberculosis (TB) infections and latent Mycobacterium
tuberculosis (MTB) infection (LTBi) remain prevalent globally. Type 2
diabetes mellitus (DM) worsens TB outcomes but the immune mechanisms
that causes this are not yet clear. We investigated a role of suppressor
of cytokine signaling molecules (SOCS1 and SOC3) in regulating host
cytokine responses in the diabetic host infected with MTB.