Mycobacterial antigen-induced IL-13 and IL-5 levels are raised
in DM-LTB cases
To investigate the effect of mycobacterial antigens on type 2 cytokines
we measured PPD-induced secretion of IL-13, IL-5 and IL-4 in DM and EC
cases with and without LTBi. PPD- stimulated IL-5 (p=0.025) levels were
found to be differ between study groups (Table 3). PPD-stimulated IL-5
levels were also raised in DM-LTBi as compared with EC (p=0.0288). IL-13
levels were significantly increased in DM-LTB as compared with DM
(p=0.0093). IL-4 secretion was not detected in the supernatants studied.