Figure 2
The figure 2a shows hyaline arteriosclerosis, which is found in the
kidney in so-called benign nephrosclerosis. Glomeruli show hypertensive
injury most likely derived from barotrauma with segmental sclerosis and
scarring (figure 2b). In cases of malignant nephrosclerosis, a pseudo
neuroendocrine atrophy pattern can be found. The disease defining change
of so-called malignant nephrosclerosis is a progressive narrowing of
interlobular arterial branches and afferent arterioles with intima
fibrosis and onion-like appearance. The oxygen supply to the glomerulus
is reduced resulting in ischemic wrinkling of the glomeruli and atrophic
tubules as shown in figure 2c. Histology pictures are kindly provided by
T. Wiech, Hamburg, Germany.