Figure 2
The figure 2a shows hyaline arteriosclerosis, which is found in the kidney in so-called benign nephrosclerosis. Glomeruli show hypertensive injury most likely derived from barotrauma with segmental sclerosis and scarring (figure 2b). In cases of malignant nephrosclerosis, a pseudo neuroendocrine atrophy pattern can be found. The disease defining change of so-called malignant nephrosclerosis is a progressive narrowing of interlobular arterial branches and afferent arterioles with intima fibrosis and onion-like appearance. The oxygen supply to the glomerulus is reduced resulting in ischemic wrinkling of the glomeruli and atrophic tubules as shown in figure 2c. Histology pictures are kindly provided by T. Wiech, Hamburg, Germany.