Statistical Analysis
All data are shown as mean ± standard error of three or more replicates. When comparing two or more groups, we used the student t -test or one-way ANOVA with post-hoc Holm-Sidak’s multiple tests for comparing selected pairwise measurements. P- values of less than 0.05 were considered statistically significant. All experiments were repeated at least twice, with similar results. For statistical analysis, GraphPad Prism ver. 7.00 (San Diego, CA) was used.