RESULTS
In our study, we researched the role of the LA strain parameters on the grading of AR. According to the grading, the patients were divided into three groups: mild, moderate, and severe AR. The basal variables among these groups are presented in Table 1. Except for gender, no statistically significant difference was noticed on other parameters among the groups.
Echocardiographic parameters are defined in Table 2. According to these parameters, end-diastolic volume (EDV) was detected to be 103.7 ±35.7 mL in the mild AR group, 119.0±40.2 mL in the moderate AR group and 167.0 ±59.7 mL in the severe AR group (p<0.001). End-systolic volume (ESV) was detected to be 39.1±16.6 in the mild AR group, 46±20.4 mL in the moderate AR group and 65.9 ±27.4 mL in the severe AR group (p < 0.001). AR vena contracta (VC) was detected to be 0.3±0.1 cm in the mild AR group, 0.4±0.1 cm in the moderate AR group and 0.7±0.1 cm (p value < 0.001) in the severe AR group. Left atrium volume (LAV) was detected to be 46.7 ±9.1 mL in the mild AR group, 46.5±10.1 mL in the moderate AR group and 59.5 ±10.7 mL in the severe AR group with a p value of 0.005.
In Table 3, left atrial mechanics are listed, and, between the groups; reservoir (42.0 ±18.0 in the mild AR group, 41.4±14.8 in the moderate AR group and 29.2 ±6.0 in the severe AR group with a p value of 0.002) and conduit (21.2 ±8.7 in the mild AR group, 19.3±7.4 in the moderate AR group and 13.1 ± 4.4 in the severe AR group (p value <0.001)), statistically significant difference was noticed, while no statistically significant difference was noticed on LA SRs, LASRe, LA SRa.
With the post-hoc Tukey analysis on the grading of AR, the p value of mild and moderate AR for the LA reservoir was determined to be 0,98, while the p value of mild and severe AR was determined to be 0,004 and the p value of moderate and severe AR was determined to be 0,02. The p value of mild and moderate AR for LA conduit was determined to be 0,69, while mild to severe AR was determined to be p <0,001 and the p value of moderate to severe AR was determined to be 0,02.
For EDV, the p value of mild to moderate AR was determined to be 0,62, whereas mild to severe AR was determined to be p <0,001 and the p value of moderate to severe AR was determined to be p 0,01. For ESV, the p value of mild to moderate AR was determined to be 0,58, whereas mild to severe AR was determined to be p <0,001 and the p value of moderate to severe AR was determined to be 0,03. For AR VC, the p value of mild to moderate AR was determined to be 0,01, while mild to severe AR was determined to be p <0,001 and moderate to severe AR was determined to be p <0,001. For LAV, the p value of mild to moderate AR was determined to be 0,99, while the p value of mild to severe AR was determined to be p 0,01 and moderate to severe AR was determined to be 0,02.