3-D representation of an HAPW followed by a SPW (HAPW-SPW) evoked in response to intraluminal prucalopride with HAPW mean amplitude of 60 mmHg and SPW mean amplitude of 25.4 mmHg was associated with anal sphincter relaxation (white arrow), nausea, strong urge to defecate and liquid expulsion. The white line shows the position of the balloon. White arrow shows partial anal sphincter relaxation.