(A) Comparison of SPW mean amplitudes at baseline and after meal intake (90 mins before prucalopride), and in response to intraluminal prucalopride. *compared to baseline (* P< 0.05).
(B) An HAPW with mean amplitude of 91 mmHg evoked by intraluminal prucalopride propagating with a velocity of 0.2 cm s-1, was associated with 92.8% anal sphincter relaxation (decrease of anal sphincter pressure from mean amplitude of 51.45 mmHg to 3.70 mmHg) as well as strong urge to defecate which likely prompted the subject to contract her external anal sphincter to avoid outflow (black arrow). The white line shows the position of the balloon, the white arrow shows the relaxed anal sphincter.
(C) 3-D representation of (B).