P: phosphorylation, P state +/-: phosphorylated or phospho-mimic and dephosphorylated or phospho-deficient respectively, W: water conductance, I: ion conductance, T: trafficking and/or protein cycling, L: protein localisation, SDM: phosphorylation or dephosphorylation mimic by site-directed mutagenesis, Pharm.: phosphorylation changes by application of pharmacological agents (kinase inhibitors or kinase activators). A ↑ or ↓ in the water or ion conductance column indicates if there was an increase or decreased observed; NE: No effect on function reported. In the expression systems column, O: Xenopus laevis oocytes; PL: proteoliposomes; PLB: planar lipid bilayers; KC: kidney cells; LLC: LLC-PK1 cells; AC: astrocyte cells; SP: spheroplasts; PP: protoplasts; IN: in vivo , IP: in planta . A blank box indicates it has not been reported on/tested.¹ Eto et al., 2010;² Lu et al., 2008;³ Moeller et al., 2010;⁴ Van Balkom et al., 2002;⁵ Hoffert et al., 2006;⁶ Hoffert et al., 2008;⁷ Moeller et al., 2010⁸ Fenton et al., 2008;⁹ Zelenina et al., 2002;¹⁰ Gunnarson et al., 2005;¹¹ Zhang et al., 2007;¹² Campbell et al., 2012;¹³ Yanochko and Yool, 2002;¹⁴ Fischer et al., 2009;¹⁵ Maurel et al., 1995;¹⁶ Grondin et al., 2015;¹⁷ Prado and Maurel, 2013;¹⁸ Prak et al., 2008;¹⁹ Qing et al., 2016;²⁰ Lee et al., 1995;²¹ Weaver et al., 1994;²² Guenther et al., 2003;²³ Johansson et al., 1998;²⁴ Van Wilder et al., 2008;²⁵ Jang et al., 2014.