Pathway Total Expected Expected Hits P.Value FDR
Cell cycle 124 16.3 40 40 2.18E-08 6.92E-06
Oocyte meiosis 125 16.4 36 36 2.41E-06 0.000383
DNA replication 36 4.72 15 15 1.97E-05 0.00209
One carbon pool by folate 20 2.62 10 10 7.61E-05 0.00605
Mismatch repair 23 3.01 9 9 0.00161 0.102
Amphetamine addiction 68 8.91 18 18 0.00228 0.12
Neurotrophinsignaling pathway 119 15.6 27 27 0.00265 0.12
Biosynthesis of amino acids 75 9.83 19 19 0.00301 0.12
Progesterone-mediated oocyte maturation 99 13 23 23 0.00388 0.125
Spliceosome 134 17.6 29 29 0.00393 0.125
Long-term potentiation 67 8.78 17 17 0.00479 0.133
Melanogenesis 101 13.2 23 23 0.00505 0.133
Pyrimidine metabolism 57 7.47 15 15 0.00545 0.133
RNA transport 165 21.6 33 33 0.00786 0.179
Legionellosis 55 7.21 14 14 0.00971 0.205
Dopaminergic synapse 131 17.2 27 27 0.0103 0.205
Amoebiasis 96 12.6 21 21 0.0115 0.206
Citrate cycle (TCA cycle) 30 3.93 9 9 0.0121 0.206
mRNA surveillance pathway 91 11.9 20 20 0.0127 0.206
Glucagon signaling pathway 103 13.5 22 22 0.013 0.206
TNF signaling pathway 110 14.4 23 23 0.0144 0.206
Alanine, aspartate and glutamate metabolism 36 4.72 10 10 0.0147 0.206
Renin secretion 69 9.04 16 16 0.0149 0.206
Nucleotide excision repair 47 6.16 12 12 0.0157 0.208
HTLV-I infection 219 28.7 40 40 0.0171 0.218
Gap junction 88 11.5 19 19 0.0179 0.219
Signaling pathways regulating pluripotency of stem cells 139 18.2 27 27 0.0218 0.251
Base excision repair 33 4.32 9 9 0.0227 0.251
2-Oxocarboxylic acid metabolism 18 2.36 6 6 0.0229 0.251
Circadian entrainment 97 12.7 20 20 0.0248 0.263
IL-17 signaling pathway 93 12.2 19 19 0.0308 0.303
GnRHsignaling pathway 93 12.2 19 19 0.0308 0.303
Ubiquitin mediated proteolysis 137 18 26 26 0.0315 0.303
Kaposi’s sarcoma-associated herpesvirus infection 186 24.4 33 33 0.041 0.351
Autophagy - animal 128 16.8 24 24 0.0427 0.351
Osteoclast differentiation 128 16.8 24 24 0.0427 0.351
Valine, leucine and isoleucine degradation 48 6.29 11 11 0.0428 0.351
Fanconianemia pathway 54 7.08 12 12 0.0437 0.351
p53 signaling pathway 72 9.44 15 15 0.044 0.351
Chagas disease (American trypanosomiasis) 103 13.5 20 20 0.0442 0.351
EGFR tyrosine kinase inhibitor resistance 79 10.4 16 16 0.0482 0.37
Cocaine addiction 49 6.42 11 11 0.0489 0.37