Cashew
In 63 cashew-allergic Greek children, sIgE to the 2S albumin Ana o 3 (AUC=0.97) performed better than extracts for predicting cashew allergy.281 A markedly greater risk of a positive food challenge was observed for higher levels of sIgE to the cupins Ana o 1 and 2, and to Ana o 3 in 173 Dutch children with suspected cashew nut allergy.282 Ana o 3 discriminated between allergic and tolerant children better than extract-specific IgE with an AUC=0.94 versus 0.78. A 95% probability for a positive cashew challenge was estimated for Ana o 3-sIgE at 2.0 kU/L.283