INTRODUCTION
The pandemic caused by SARS-CoV-2, most commonly known as Coronavirus disease 2019 (COVID-19), is one of the most important challenges humanity is facing nowadays, pushing health systems around the world to maximum capacity, leading to the collapse in intensive care units [1].
Its clinical forms vary from asymptomatic to mild, moderate, and severe symptoms, leading to fatal events in many cases. One of the most common symptoms is the development of an acute respiratory disease, which can lead to respiratory or multi-organ failure [2].
Current research has identified, several risk factors for severe outcomes. The most important factors include old age, hypertension, diabetes, cardiovascular disease, tobacco exposure, malignancies, and immunosuppression [3]. Initially, asthma was thought to be a risk factor for SARS-CoV-2 infection, as COVID -19 primarily affects the respiratory system; surprisingly, many are the reports, and large case series published that remark the low prevalence of asthma among COVID -19 patients [4-8], including those admitted in the intensive care unit, who required mechanical ventilation (1.8%) [9].
The main purpose of this study is to analyze the personal characteristics in severe asthma patients in treatment with monoclonal antibody (MAB), belonging to the Health Department of Castellon’s University General Hospital, (Castellon, Spain), in order to see which behavioral and social circumstances obey patients, and if these variables affect in any way the probability of being infected by COVID-19 or not. Secondly, we wanted to investigate the prevalence of COVID-19 in these patients.