Raw data statistics
The total sequence data of 12 stool samples from three sojourners at four time points were 20 Million average reads and an average read length 2x150 bp (Supplementary Figure S1(a)). Stool samples from remaining 16 participants (32 samples) were analyzed by 16S rRNA sequencing for H1 and H2 heights (Supplementary Figure S1 (b)). Using MiSEQ an average of reads and read length 126000 and 2x250 bases, respectively, was generated.
The raw abundance profile from WGS data (MOTUs) of 12 samples (Supplementary Figure S2(a) and abundance profile of OTUs from 16s rRNA data of 32 samples were normalized and transformed by using TSS (CSS+Log2) (Supplementary FigureS2(b)).