Study population
The study population was randomly selected in the pregnant women
presented to our center from July 2018 to December 2019. Fetuses with
confirmed CHD or extracardiac abnormalities were excluded. Mothers with
gestational anemia, diabetes, hypertension, and other high-risk factors
were also excluded. All fetuses involved were singletons. In total, 123
pregnant women were enrolled in this study. Maternal gestation age
ranged from 20 to 37 weeks. Informed consent was obtained from each
patient and the study was approved by the Ethics Committee of Shengjing
Hospital of China Medical University. All cases underwent a month
postnatal echocardiography follow-up.