All (n = 172) No event group (n = 157) AA event group (n = 15) P
Age, year 61.6 ± 13.3 61.4 ± 13.5 63.7 ± 11.0 0.52
Male, n (%) 105 (61) 94 (59) 11 (73) 0.41
Body surface area, m2 1.62 ± 0.22 1.61 ± 0.22 1.64 ± 0.22 0.59
Hypertension, n (%) 85 (49) 77 (49) 8 (53) 0.96
Diabetes mellitus, n (%) 18 (10) 15 (10) 3 (20) 0.19
Hypercholesterolemia, n (%) 52 (30) 48 (31) 4 (27) 0.98
Smoking, n (%) 51 (30) 46 (29) 5 (33) 0.98
Coronary artery disease, n (%) 23 (13) 19 (12) 4 (27) 0.24
Chronic kidney disease, n (%) 14 (8) 14 (9) 0 (0) 0.48
NYHA 0.32
47 45 2
96 87 9
24 20 4
5 5 0
Echocardiographic data
LV mass index, g/m2 116 ± 32 115 ± 32 121 ± 28 0.59
LV end-diastolic diameter, mm 53.3 ± 6.1 53.4 ± 6.2 51.9 ± 5.4 0.36
LV end-systolic diameter, mm 33.4 ± 6.1 33.5 ± 6.3 32.2 ± 3.7 0.42
LV ejection fraction, % 64.6 ± 8.7 64.4 ± 9.0 66.4 ± 5.4 0.42
LA diameter, mm 41.4 ± 6.7 41.5 ± 6.7 41.9 ± 6.8 0.85
TR peak pressure gradient, mmHg 32.6 ± 15.5 32.3 ± 14.9 35.0 ± 20.0 0.59
Aorto-mitral angle, degree 134 ± 11 135 ± 11 131 ± 12 0.29
Etiology of MR
Prolapse due to FED, n (%) 150 (87) 135 (86) 15 (100) 0.61
Anterior mitral leaflet prolapse, n (%) 59 (34) 50 (32) 9 (60) 0.051
Posterior mitral leaflet prolapse, n (%) 111 (65) 104 (66) 7 (47) 0.08
Barlow’s disease, n (%) 3 (2) 3 (2) 0 (0) 1
Rheumatic, n (%) 1 (1) 1 (1) 0 (0) 1
Secondary MR, n (%) 4 (2) 4 (3) 0 (0) 1