Conclusion
In our meta-analysis an association between OSA and DD was detected that
appears independent of conventional cardiovascular risk factors.
Investigation of OSA in HFpEF patients and conversely echocardiographic
testing in OSA patients to screen for HFpEF is recommended. On the other
hand, early application of OSA treatments might lead to more favorable
outcomes in this therapeutically challenging clinical setting. Large
prospective studies are warranted to demonstrate whether this approach
confers more optimal long-term clinical outcomes.