Fluoroquinolone Effectiveness
Sixty-five children (86%) were successfully treated with an enteral
fluoroquinolone, without antibiotic duration extension, change in
antibiotic regimen, or readmission or initiation of a new antibiotic for
a LRTI within 30 days of fluoroquinolone completion (Table 4). Eight
(11%) were readmitted for a respiratory-related condition within 30
days of enteral fluoroquinolone completion. One of these patients was
treated with a fluoroquinolone that did not provide adequate coverage of
an organism isolated in their culture. Fluoroquinolone duration was
extended by seven days and changed to a different antibiotic for one
patient each. A new antibiotic course was prescribed for pulmonary
infection for 10 (13%) patients within 30 days of fluoroquinolone
completion. Four of these antibiotic regimens included an enteral
fluoroquinolone.