Fluoroquinolone Effectiveness
Sixty-five children (86%) were successfully treated with an enteral fluoroquinolone, without antibiotic duration extension, change in antibiotic regimen, or readmission or initiation of a new antibiotic for a LRTI within 30 days of fluoroquinolone completion (Table 4). Eight (11%) were readmitted for a respiratory-related condition within 30 days of enteral fluoroquinolone completion. One of these patients was treated with a fluoroquinolone that did not provide adequate coverage of an organism isolated in their culture. Fluoroquinolone duration was extended by seven days and changed to a different antibiotic for one patient each. A new antibiotic course was prescribed for pulmonary infection for 10 (13%) patients within 30 days of fluoroquinolone completion. Four of these antibiotic regimens included an enteral fluoroquinolone.