Antimicrobial Coverage
Of 224 organisms isolated from 82 cultures, 131 (58%) were susceptible
and 18 (8%) resistant to the fluoroquinolone used based on the
patient-specific susceptibility report. Fluoroquinolone susceptibility
of 75 (33%) organisms was not reported. Of these, 17 (23%) were
presumed susceptible, 14 (19%) were not presumed susceptible but an
additional antibiotic was used with appropriate coverage, and 20 (27%)
organisms were not susceptible to the fluoroquinolone used, with no
additional antibiotic utilized13. Of the 14 organisms
resistant to the fluoroquinolone used but treated with an additional
antibiotic that provided coverage of the resistant isolate, 10 (67%)
were treated during or for at least 5 days immediately prior to the
fluoroquinolone course. Twenty-four (32%) organisms without reported
fluoroquinolone susceptibility were considered nonpathogenic.
In total, 172 (77%) bacterial isolates were treated with antibiotics
with known or presumed appropriate activity; including organisms
considered likely nonpathogenic (n=24, 32%), 196 (88%) of the 224
organisms were treated with agents with known or presumed antimicrobial
activity. Twenty-eight (13%) isolates did not have appropriate
antibiotic coverage provided.