Antimicrobial Coverage
Of 224 organisms isolated from 82 cultures, 131 (58%) were susceptible and 18 (8%) resistant to the fluoroquinolone used based on the patient-specific susceptibility report. Fluoroquinolone susceptibility of 75 (33%) organisms was not reported. Of these, 17 (23%) were presumed susceptible, 14 (19%) were not presumed susceptible but an additional antibiotic was used with appropriate coverage, and 20 (27%) organisms were not susceptible to the fluoroquinolone used, with no additional antibiotic utilized13. Of the 14 organisms resistant to the fluoroquinolone used but treated with an additional antibiotic that provided coverage of the resistant isolate, 10 (67%) were treated during or for at least 5 days immediately prior to the fluoroquinolone course. Twenty-four (32%) organisms without reported fluoroquinolone susceptibility were considered nonpathogenic.
In total, 172 (77%) bacterial isolates were treated with antibiotics with known or presumed appropriate activity; including organisms considered likely nonpathogenic (n=24, 32%), 196 (88%) of the 224 organisms were treated with agents with known or presumed antimicrobial activity. Twenty-eight (13%) isolates did not have appropriate antibiotic coverage provided.