Abstract
Background and Purpose
Inhibition of NLRP3 inflammasome plays a critical therapeutic potential in the colonic inflammatory responses. The Timosaponin BⅡ (TBⅡ) isolated from the traditional Chinese medicine Anemarrhena asphodeloides has outstanding anti-inflammatory effects in a variety of diseases. Here, we investigated the protective effects of TBⅡ against dextran sulfate sodium (DSS)-induced ulcerative colitis in mice.