2.11 Data and statistical analysis
The data and statistical analysis in this study comply with the recommendations of the British Journal of Pharmacology on experimental design and analysis in pharmacology (Curtis et al., 2018). Data were expressed as mean ± standard error of the mean (SEM). Statistical analyses were evaluated using GraphPad Prism 8.0 software(GraphPad Software, San Diego, CA, USA). Significant differences between groups were determined using a one-way ANOVA with Dunnett’s multiple comparisons test with no significant variance inhomogeneity.P < 0.05 was considered statistically significant.