Abstract
Background
and Purpose
Inhibition of NLRP3 inflammasome plays a critical therapeutic potential
in the colonic inflammatory responses. The Timosaponin
BⅡ (TBⅡ) isolated from the
traditional Chinese medicine Anemarrhena asphodeloides has
outstanding anti-inflammatory effects in a variety of diseases. Here, we
investigated the protective effects of TBⅡ against dextran sulfate
sodium (DSS)-induced ulcerative colitis in mice.