3 RESULTS
3.1 Overall proteomic analysis of brain tumors
In an attempt to analyze the proteome of primary and secondary tumors, we assembled the most common primary tumors as follows (Figure 1): gliomas from WHO grade II to IV with or without IDH1 mutations; and BrMs with a wide range, including lung cancer (L.C), breast cancer (B.C), ovarian cancer (O.C), and colorectal cancer (C.C). Figure 2A and B, as well as Table S1 provide additional details for the assembled cohort and MRI for diagnosis.