Other medications included in the reports
The reported cases included a total of 2,263 drugs, including HCQ. Accordingly, on average, each patient was administered 3.6 medications, and the number of drugs given to Covid patients was larger than that given to their no-Covid counterparts. More than 90% of Covid patients took more than one medication relative to the group of no-Covid patients, in which this percentage was less than 50%. Table 1 displays the groups of drugs that were most frequently notified together with HCQ. Figure 2 shows, according to their active ingredient, the drugs notified along with HCQ that were deemed to be suspected either by themselves or due to their potential interactions.
Reported adverse drug reactions
Organs and systems most frequently affected in reported cases were as follows: hepatobiliary disorders (133 cases, 21%), gastrointestinal disorders (124 cases, 20%), skin and subcutaneous tissue disorders (123 cases, 19%), and cardiac derangements (80 cases, 13%). Figure 3 shows the distribution of the involved organs / systems according to the corresponding percentages of notified cases separately for Covid and no-Covid patients.