Timeline of the symptoms
In most of the subgroups analysed, there was a slight predominance in
the occurrence of a single symptom at disease onset relative to
individuals with a bi-symptomatic onset or that involving a triad of
symptoms. This was not the case in model 3 of clinical evolution, where
the difference between the occurrence of a single symptom and the
occurrence of the triad of symptoms at disease onset was much
greater.(Table 1).