Materials and Methods
Our hospital is a tertiary university hospital that performs the
isolation of BMT patients before and after their transplantation and
their treatment during this isolation. Strengthening the Reporting of
Observational Studies in Epidemiology (STROBE) guidelines were followed
for this original observational retrospective study designed based on
data collected from our hospital records. BMT was applied to 451
patients between March 2014 and October 2018 in our hospital’s adult
hematology clinic. Our ORL clinic received 30 consultations from these
BMT patients at that time. All these patients had BMT for different
diagnosis. Depending on their diagnosis and stem cell sources, some
patients had TBR prior to BMT, while others received chemotherapy for
bone marrow suppression. After BMT, all patients had different lengths
for immunosuppressive therapy to prevent rejection and complications.
All patients were isolated in the hospital and followed closely until
their immune system reached a certain level and the side effects caused
by the treatment were controlled. ORL problems and their treatment
processes, which are the subject of our study, include this isolation
process. Patients’ applications that developed after discharge and made
outpatient were not included in the study. If the patient was
re-hospitalized for a condition that developed in the future and a new
BMT was not performed, the consultations performed for these patients
were also excluded from the study. Ethical institution name is blinded
for review.
Statistical analyses
Differences were evaluated using ANOVA and chi-square tests as
appropriate. A chi-square test was used to test the similarity of gender
distribution. The differences between the age of the patients, the
duration of the ORL consultation between transplant and ORL examination
were evaluated using the One-way ANOVA F test, considering gender
characteristics. Data were analyzed using SPSS Statistics version 22.0
(IBM, New York, USA) and Microsoft Excel® 2010 software. Statistical
significance was accepted as p <0.05.