Corticosteroids |
Bind glucocorticoids receptors (GR)and exert
profound immune-modulatory actions |
Inhibit the hypothalamic-
pituitary-adrenal (HPA) axis, skin atrophy, osteoporosis, obesity,
hypertension, diabetes, immunosuppression |
Allergic asthma, contact
dermatitis, allergic rhinitis, drug and food allergies |
Antihistamines |
Block histamine H1 receptor and inhibit the
inflammatory response mediated by adhesion molecules |
Drowsiness,
arrhythmia, liver toxicity, gastrointestinal reaction |
Allergic asthma,
allergic rhinitis,contact dermatitis and food allergy |
β2-adrenergic agonists
|
Activate β2 receptors to relax smooth muscles, increase mucociliary
clearance, and reduce vascular permeability
|
Tachycardia, hypokalemia
|
Allergic asthma, allergic rhinitis
|
Anticholinergics |
Promote relaxation of airway smooth muscle |
Thick sputum, blurred vision |
Allergic asthma, allergic
rhinitis |
Theophylline (1,3-dimethylxanthine) |
Inhibit non-specific
phosphodiesterase (PDE) and antagonizes adenosine receptors |
Palpitations, headaches, vomiting |
Allergic asthma, allergic
rhinitis |
Antileukotrienes |
Inhibition of leukotriene receptors |
Headache, rash, nausea, vomiting, leukopenia, thrombocytopenia |
Allergic asthma, allergic rhinitis |
Trx1 |
Antioxidation, inhibit macrophage migration inhibitory
factor (MIF), regulate Th1/Th2 immune balance, modulate allergic
inflammatory cells, and suppress complement activation |
Not found yet |
Allergic asthma, contact dermatitis, allergic rhinitis, drug and food
allergies |