Introduction
Waldenström’s macroglobulinemia (VM) is a low-grade B cell
lymphoproliferative disorder characterized by a monoclonal synthesis and
secretion of immunoglobulin M (Ig M) [1, 2]. Neurologic symptoms are
commonly a part of hyperviscosity syndrome or autoimmunologic processes
[1, 4]. Rarely, they may result from a direct infiltration of the
central nervous system (CNS) by lymphoplasmatoid cells and thus defines
the Bing-Neel syndrome (BNS) [1, 2, 3, 4]. This CNS metastasis is
commonly a diffuse spreading and a focal tumor like presentation is very
rare with usually small size lesions [2, 3 4]. An appearance of a
genuine extra axial tumor is very rare in the literature and to the best
of our knowledge only 3 cases has been found. We report an incidental
discovery of a huge fronto-parietal lesion mimicking a meningioma and
referable to a Bing-Neel syndrome after pathological and biological
investigations.