Left Ventricular Metastasis presenting 15 years after excision
of Right Thigh Myxoid Liposarcoma
[Author: Sanchit V. Kundal1, M.D., Hong Yu
Wang2, M.D., Samuel Tan2, Wenchy
Tan2, Maria Riasat2, M.D., Deepika
Misra1, M.D.]
Institutional Affiliations [1. Department of Cardiology, Icahn School
of Medicine at Mount Sinai, Mount Sinai Beth Israel 2. Department of
Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth
Israel]
Author’s contributions:
SK was responsible for concept of the article and drafted and revised
the manuscript. HW was responsible for the conception of the article and
revised the manuscript. ST, WT, and MR contributed revising of the
manuscript. DM contributed to the conception of the article, the
drafting and revising of the manuscript.
Conflict of Interest Disclosures: There are no conflicts of interest
disclosure for all authors.
Acknowledgement: N/A
Abstract/Introduction
While both primary and secondary cardiac tumors are extremely rare,
tumors found in the heart are more likely to be metastatic lesions from
other organs. Myxoid liposarcoma is second most common type of
liposarcoma in adults, usually presenting in deep tissue of the lower
extremities. Myxoid liposarcoma is known to have an unusual tendency for
extrapulmonary metastasis. However, the link between myxoid liposarcoma
and cardiac metastasis are rare. We report a case of a 49-year-old
female with myxoid liposarcoma of the right thigh with metastasis to
left ventricle of the heart fifteen years after initial excision.
Keywords : Cardiac tumor, Liposarcoma, Myxoid liposarcoma,
Cardiac metastasis
Abbreviations :
Transthoracic echocardiography (TTE)
Cardiac magnetic resonance imaging (MRI)
Positron emission tomography–computed tomography (PET/CT)
Case Presentation/Examination
49-year-old female with past medical history of hypertension, tobacco
and marijuana use, presented to the ER with complaints of intermittent
palpitations for 2 weeks. On the day of presentation the palpitations
were more frequent and associated with new onset shortness of breath
along with lightheadedness. Initial physical examination and vital signs
were unremarkable. EKG showed sinus rhythm, premature ventricular
contractions with T-wave inversion in leads V3-V6 and II, III, aVF.
Patient reported being diagnosed with sarcoma of right thigh in May
2007, and its subsequent removal in August 2007. She followed up with
oncology afterwards and remained in remission. Her clinical history also
relevant for hypertension, tobacco and marijuana smoking and
gastro-esophageal reflux disease. Patient denied any significant family
history of cardio-pulmonary disease.
Methods