Left Ventricular Metastasis presenting 15 years after excision of Right Thigh Myxoid Liposarcoma
[Author: Sanchit V. Kundal1, M.D., Hong Yu Wang2, M.D., Samuel Tan2, Wenchy Tan2, Maria Riasat2, M.D., Deepika Misra1, M.D.]
Institutional Affiliations [1. Department of Cardiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel 2. Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel]
Author’s contributions:
SK was responsible for concept of the article and drafted and revised the manuscript. HW was responsible for the conception of the article and revised the manuscript. ST, WT, and MR contributed revising of the manuscript. DM contributed to the conception of the article, the drafting and revising of the manuscript.
Conflict of Interest Disclosures: There are no conflicts of interest disclosure for all authors.
Acknowledgement: N/A
Abstract/Introduction
While both primary and secondary cardiac tumors are extremely rare, tumors found in the heart are more likely to be metastatic lesions from other organs. Myxoid liposarcoma is second most common type of liposarcoma in adults, usually presenting in deep tissue of the lower extremities. Myxoid liposarcoma is known to have an unusual tendency for extrapulmonary metastasis. However, the link between myxoid liposarcoma and cardiac metastasis are rare. We report a case of a 49-year-old female with myxoid liposarcoma of the right thigh with metastasis to left ventricle of the heart fifteen years after initial excision.
Keywords : Cardiac tumor, Liposarcoma, Myxoid liposarcoma, Cardiac metastasis
Abbreviations :
Transthoracic echocardiography (TTE)
Cardiac magnetic resonance imaging (MRI)
Positron emission tomography–computed tomography (PET/CT)
Case Presentation/Examination
49-year-old female with past medical history of hypertension, tobacco and marijuana use, presented to the ER with complaints of intermittent palpitations for 2 weeks. On the day of presentation the palpitations were more frequent and associated with new onset shortness of breath along with lightheadedness. Initial physical examination and vital signs were unremarkable. EKG showed sinus rhythm, premature ventricular contractions with T-wave inversion in leads V3-V6 and II, III, aVF.
Patient reported being diagnosed with sarcoma of right thigh in May 2007, and its subsequent removal in August 2007. She followed up with oncology afterwards and remained in remission. Her clinical history also relevant for hypertension, tobacco and marijuana smoking and gastro-esophageal reflux disease. Patient denied any significant family history of cardio-pulmonary disease.
Methods