Fig 1. CXCR1 and CXCR2 stimulate allergen challenge-induced
allergic lung inflammation
(A ) Protocol for CDE-MCM with or without ladarixn treatment.
(B ) Protocol for CDE-SCM with or without ladarixin treatment.
(C ) The levels of BALF neutrophils at 16 h post-CDE challenge
in CDE-SCM. (D ) The numbers of inflammatory cells in BALF at 72
h post-CDE challenge in CDE-MCM. (E ) FCM analysis of the
numbers of inflammatory immune cells in the lungs at 72 h post-CDE
challenge in CDE-MCM. (F ) The levels of serum total IgE and
CDE-specific IgE at 72 h post-CDE challenge in CDE-MCM.
BALF; bronchoalveolar lavage fluid
CDE; cat dander extract
CDE-MCM; CDE-multiple challenge model
CDE-SCM; CDE-single challenge model