Aim To observe the clinical effect of small splint fixation and Gukangling-Fluid in the treatment of patients with closed trauma fractures. Materials and Methods Methods: the patients were divided into two groups: 350 cases of Gukangling-Fluid treatment group and 84 cases of conventional western medicine plaster control group. Results Results statistically significant difference was found between the two groups (P<0.001). The total effective rate of the experimental treatment group was 92 %, and that of the conventional western medicine control group was 72 %. Conclusion Gukangling-Fluid has a good effect on the treatment of closed fracture.